Cognitive
health

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Our cognitive health describes how our brain helps us to interact socially, process information, think, make decisions, stay alert, focus, and create and recall memories.

All these functions require a lot of energy. Our modern, stressful and unhealthy lifestyles negatively impact the way that our brain produces energy.

By improving energy efficiency in brain cells, we can improve their ability to sustain these important cognitive functions.

The brain uses glucose as a primary source of energy.

Insulin is a hormone that helps our cells use glucose for energy.

The brain is an insulin sensitive organ. If the action of insulin is impaired in the brain, this may lead to a mismatch between the high amount of energy needed for cognitive functions and the amount of energy produced.  This has been called the brain energy gap.

At the heart of energy production are mitochondrial substrates. Succinate is one of them. Our new choline salt solution (DISU™ - choline + succinic acid) helps to generate the energy to unlock the "door" to the cell (insulin receptor). It works together in combination with Nicotinamide, another required mitochondrial substrate.

The Statistics

$40B

brain health functional F&B markets by 2030

10.5%

expected CAGR by 2030

Imagine a solution designed to enhance the brain's energy production and improve its ability to support the action of insulin.

Mitocholine does just that by combining carefully chosen ingredients that work together to improve energy production by the mitochondria – helping insulin to unlock the cell and let glucose inside. One of our ongoing, double-blind, randomized, placebo-controlled trials is studying Mitocholine’s impact on important cognitive outcomes, in people with mild cognitive impairment (MCI), when taken daily over 16 weeks. There is a growing body of evidence demonstrating that improving cellular energetics may attenuate the onset of dementia and other neurodegenerative diseases (e.g. Alzheimer's disease and Parkinson's). By targeting both the action of insulin and mitochondrial function, we pave the way for enhancing brain energy and vitality in our hectic modern lives.

The global brain health functional food and beverage market is expected to reach $40B by 2030 with a CAGR of 10.5%. This is from a base of $18.1B in 2022. Supplements for brain health have been valued at 8.9B in 2022 and expected to reach $23.9B in 2032 with a CAGR of 10.2%. Key factors that are driving the brain health supplements market growth include rising concerns among consumers over brain health issues such as memory enhancement, alertness, creativity, motivation, and attention.

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